Overweight In Middle Age Tied To Low Breast Cancer Risk

While obesity has been shown to increase breast cancer risk in elderly, for younger women the opposite seems to be true. For pre-menopausal women, a higher body fat was linked to lower breast cancer risk, according to researchers.

The study, published in the journal JAMA Oncology, showed that there was 23 per cent lower breast cancer risk linked to each five-unit increase in body mass index (BMI) between the ages of 18 and 24.

At ages 25 to 34, each five-unit increase in BMI was linked to 15 per cent lower risk.

There was a 13 per cent lower risk for BMI at ages 35 to 44, and a 12 per cent lower risk for BMI at ages 45 to 54 years.

Read: Want to gain weight? Include these 10 foods in your diet

“We saw a trend where, as BMI went up, cancer risk went down. There was no threshold at which having a higher BMI was linked to lower cancer risk,” said Hazel B. Nichols, assistant professor at the University of North Carolina.

The trend could be attributed to multiple factors such as differences in hormones, including estrogen — primary female sex hormone — growth factors, or breast density, Nichols said.

Estrogen has known to be a key driver of breast cancer. But, the small amount of estrogen produced by fat tissue before menopause may help tell the ovaries that they can produce less estrogen and also regulate other hormones or growth factors, Nichols said, adding that after menopause, women with higher adipose tissue have higher estrogen levels and usually a higher breast cancer risk.

“In young women, estrogen is one factor that contributes, but it’s not the whole story,” she noted.

Read: Does running and jogging cause weight gain?

For the study, the team pooled data from 19 different studies to investigate breast cancer risk for a group of 758,592 women who were younger than 55 years.

However, “this study is not a reason to try to gain weight to prevent breast cancer. Heavier women have a lower overall risk of breast cancer before menopause, but there are a lot of other benefits to managing a healthy weight that should be considered,” Nichols noted.

Source: IANS

Image Source: Shutterstock

Source : https://www.thehealthsite.com/news/overweight-in-middle-age-tied-to-low-breast-cancer-risk-ag0618/

loading...
Overweight in middle age tied to low breast cancer risk
Higher body fat linked to lower breast cancer risk in younger women
Low Muscle Mass Tied to Death Risk in Early-Stage Breast Cancer
Weight loss after menopause tied to lower breast cancer risk
Weight Loss Tied to Lower Risk of Uterine Cancer
Belly fat increases risk of breast cancer despite normal BMI, study finds
Regular exercise after menopause tied to lower breast cancer risk
Birth Control Tied to Rise in Breast Cancer Risk